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4 grams/kg daily for up to 6 months has been taken safely in both infants and children. The cells in your skeletal muscles, heart muscles or brain release creatine kinase into your blood when they’re damaged. Even within the scientific literature creatine supplementation in adolescents has inappropriately been classified as “unhealthy behavior” , “disturbing trends” , or has been compared to illegal performance enhancing drug use without any supporting evidence of its dangers or scientific rationale for such a classification. It doesn’t provide a full picture of your health, so healthcare providers typically perform other tests to make a diagnosis. Although an older case study suggested that creatine might worsen kidney dysfunction in people with kidney disorders, creatine doesn't appear to affect kidney function in healthy people. There is no evidence to support any significantly detrimental side effects in people who consume high doses of creatine (30 grams/day) for up to 5 years ( 2 ).
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